Faster DNA sequencing

Screened DNA packs faster.

Despite being negatively charged, DNA can be compacted to almost crystalline densities inside virus capsids. However, how this is achieved has been debated for years. Most theoretical models predict that attractive DNA–DNA interactions — such as those resulting from the screening effect of nearby positively charged molecules — would facilitate DNA packaging by countering the effects of DNA self...

DNA Sequencing

Double stranded DNA sequencing as a choice for DNA sequencing.

Double stranded DNA sequencing (1) is favored because of its simplicity, and convenice. However it is only recently that the quality of this method has become comparable with single stranded DNA sequencing. We believe that two factors have limited the popularity of double stranded DNA sequencing: 1, the quality of the template DNA; 2, the inherent propertv.,of the DNA polymerase. The modified T...

DNA sequencing: clinical applications of new DNA sequencing technologies.

We are in a time of great change in genetics that may dramatically impact human biology and medicine. The completion of the human genome project,1,2 the development of low-cost, high-throughput parallel sequencing technology, and large-scale studies of genetic variation3 have provided a rich set of techniques and data for the study of genetic disease risk, treatment response, population diversi...

ParDRe: faster parallel duplicated reads removal tool for sequencing studies

UNLABELLED Current next generation sequencing technologies often generate duplicated or near-duplicated reads that (depending on the application scenario) do not provide any interesting biological information but can increase memory requirements and computational time of downstream analysis. In this work we present ParDRe, a de novo parallel tool to remove duplicated and near-duplicated reads t...